During recent years, a member of Flaviviridae family named Zika virus emerged as a prominent human pathogen mostly because of its connection with neonatal microcephaly. While the effect of Zika virus infection on pregnant women especially neuronal development of fetus is well proven, the molecular mechanism behind this in cellular level was not understood. In a recent report in Science, Chavali et al. first time revealed the molecular mechanism behind the effect of Zika Virus Infection on neurodevelopment (Chavali et.al., 2017).