‘Micro’-management of Obesity and Cancer | Society of Life Sciences (SoLS)

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ISSN : 2328-9791

‘Micro’-management of Obesity and Cancer

Lathika Mohanraj and Debra E. Lyon

Virginia Commonwealth University

Department of Family and Community Health Nursing, School of Nursing, Virginia Commonwealth University, Richmond, VA 23298–0567, USA

mohanrajl@vcu.edu

Recent decades have witnessed the emergence of diseases that tend to occur simultaneously and are often inter-related in more than one ways. Metabolic syndrome has come to be a dominant concern primarily in the developed countries and the incidence rate under this umbrella of disorders is constantly increasing. Another equally prevalent and life-changing disease, cancer is also on the rise and the National Cancer Institute (NCI) estimates that as of January1, 2012, approximately 13.7 million Americans living have had a history of cancer. Extensive research has been done at the clinical, translational and molecular level and numerous inter-connections have been established and proposed between the two morbid conditions metabolic syndrome and cancer. MicroRNAs (miRNAs) have more recently emerged on the research arena and present a whole new array of possible approaches and mechanisms that could potentially provide answers to numerous questions at the molecular level. This review focuses on.........