Availing the opportunity to get an independent research grant at the postdoctoral level not only provides encouragement and stability but also opens up new avenues of research and academic success. Awareness about research grants in terms of availability, eligibilities as well as a good research plan increases the chance of success. The present article is inspired by my research experiences in the United States. I tried to compile the sources for research grants, their eligibilities, and provide basic knowledge about how to design and write a proposal that will have the best chance for success. In my opinion this commentary will benefit the early stage researchers, especially non-immigrant researchers within the United States.